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Description
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Glutathione has been termed the master antioxidant because of its ability to quench free radicals and protect cells from damage
[,,,] Most importantly, AGT also has directly biological activities
Senescent cells promote inflammation and fibrosis by activating the p16/p21-Rb pathway and secreting senescence-associated secretory phenotype (SASP) factors, including IL-1, IL-6, IL-8, TGF-, plasminogen activator inhibitor (PAI), and insulin-like growth factor-1(IGF-1) (Lin et al., 2022
Table 2 Clinical trials of anti-angiogenic targeted tyrosine kinase inhibitors in the treatment of gastric cancer
