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Description
Norris, M
Qingchang Wenzhong Decoction reduce ulcerative colitis in mice by inhibiting Th17 lymphocyte differentiation
discovred two compouds, 2-[1-hydroxy-2-oxo-2-phenylethyl]sulfanyl acetic acid and 4-[furan-2-yl]methyl amino-1,2-diazinane-3,6-dione, demonstrated cancer-cell-type-selective antiproliferative effects in selected leukemia cell lines
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This is due to an impairment in dTMP synthesis which leads to cell cycle arrest in S-phase of rapidly proliferating cells, in particular hematopoietic cells
