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Regulation of mediator release by human basophils: importance of the sequence and time of addition in the combined action of different agonists

In this narrative review, we address oxidative stress as a major driver of pathophysiologic processes in cartilage and bone, including senescence, misdirected differentiation, cell death, mitochondrial dysfunction, and impaired mitophagy by illustrating the consequences on tissue homeostasis and regeneration

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Keywords: Vasoactive Intestinal Peptide, VIP, VPAC ABSTRACT Vasoactive intestinal peptide (VIP) is a 28-amino acid polypeptide first isolated from swine duodenum

When this process becomes disrupted, and the breakdown exceeds the ability to repair, symptoms, degeneration, and chronic conditions occur