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10.1038/nrd.2017.16 36 NakagawaS.KimJ.-E.LeeR.MalbergJ

Meanwhile, researchers discovered Mitochondria-targeted antioxidants (MTAXs) that can improve mitochondrial functions and antioxidant activity through the modulation of mitochondrial signaling pathways, including peroxisome proliferator-activated receptor (PPAR)-coactivator 1 (PGC-1), dynamin-related protein 1 (Drp1), mitochondrial fission protein 1 (Fis1), and Silent mating type information regulation 2 homolog 1 (SIRT-1), showing neuroprotective effects in HD

[Google Scholar] 139.Rastogi R., Srivastava A.K., Rastogi A.K

We speculate that this may be because diets with Lys/Met ratios of 3:1 and 2:1 promote the expression of lipolysis-related genes