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Semax does not appear to cause traditional tolerance in the way stimulants do, though receptor sensitivity adjustments may occur with prolonged continuous use

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Profiling of Plasma Metabolites Suggests Altered Mitochondrial Fuel Usage and Remodeling of Sphingolipid Metabolism in Individuals With Type 2 Diabetes and Kidney Disease

doi: 10.1016/j.neurobiolaging.2013.11.001 251 BraakHSastreMBohlJREde VosRAITrediciKD

Abstract The expression of glutathione S-transferase P1 (GSTP1) enzyme increases in cancer cells, leading to anticancer drug resistance
