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Engineered variants of LpoB were produced in the background of a truncation used for affinity maturation (LpoB 64-213 , pSI259) to match yeast selection conditions

They do not exhibit any pleomorphism and are located between dermal collagen bundles, which may appear slightly thickened

A lower ratio usually means a lower risk of heart disease, while a higher ratio can suggest more strain on your heart and blood vessels

Then, the behavior in response to odor presentation was evaluated following MC4R antagonist or vehicle injection into the amOT using the same procedures as in the MC4R agonist experiments

doi: 10.1002/14651858.CD006095.pub3