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If density declines significantly, interventions include calcium and vitamin D optimization, weight-bearing exercise, and sometimes pharmacologic therapy

As noted by Kraus et al., Nature Medicine and Ng et al., Journal of Endocrinology , targeting both systemic metabolism and localized fat cell activity may enhance fat-loss outcomes beyond either approach alone
Regular blood tests help us see if the current dose is right

THF may be regenerated via MTR or may be obtained from fresh folate in the diet
Vitamins in Animal and Human Nutrition (2nd ed.)
