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IDH-305 is in phase I trials for malignancies with IDH R132 mutations (NCT 02381886)
Cancer-related concerns with specific compounds Dihexa activates the HGF/c-Met pathway, which is a known oncogenic signaling axis
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[DOI] [PubMed] [Google Scholar] 499.Dolui S, Detre JA, Gaussoin SA, Herrick JS, Wang DJJ, Tamura MK, Cho ME, Haley WE, Launer LJ, Punzi HA, Rastogi A, Still CH, Weiner DE, Wright JT, Williamson JD, Wright CB, Bryan RN, Bress AP, Pajewski NM, Nasrallah IM
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