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Description
In hepatic metabolism, the CYP450 enzymes convert artemisinin into metabolites for easier excretion through oxidation, reduction, and hydrolysis processes ( via hydroxylation and sulphonation, these metabolites then pass into the bloodstream through the liver and kidneys before being eliminated from the body
Reinforces antioxidant defense mechanisms

In Canada, the UK, and the EU , MK-677 is similarly restricted to research-only status

& Boyne, M

Hollenstein K, de Graaf C, Bortolato A, Wang MW, Marshall FH, Stevens RC
