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Several polyphenols have been identified as histone deacetylase (HDAC) inhibitors (EGCG, curcumin, genistein, quercetin), histone acetyltranferase (HAT) activators (genistein) or HAT inhibitors (EGCG, curcumin) (104)

258 Studies have shown that curcumin can reduce TMAO production by regulate the abundance, diversity, and composition of gut microbiota, thereby regulating macrophage polarization and mitigating cadmium-induced atherosclerosis in mice

By increasing Nrf2 expression, Met suppresses metabolic stress-induced myocardial inflammation and lipid accumulation in HF-fed mice [21]

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Thiazolidinediones in prediabetes and early type 2 diabetes: what can be learned about that diseases pathogenesis