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Supporting this mechanistic role, observational studies indicate that initial carnitine uptake and serum L-carnitine levels in preterm infants during the early postnatal weeks are independently associated with brain size

Table 3 Characteristics of patients with prurigo pigmentosa induced by the KD

Documented side effects include: Nausea and flushing after injection

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In line with these observations in rodents, human genetic studies published in the early 2000s identified MC4R mutations as the most common monogenic cause of obesity, affecting up to 6% of individuals with severe obesity (36)