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Conclusion Since we now found that only a small percentage of CMD patients have abnormal low levels of LH, FSH and/or TSH between lGF-1 levels of 84100 /l, we cautiously propose that IGF-1 low levels may be too low to be considered as an independent diagnostic marker to treat AGHD with CMD patients

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Intragastric and oral administration give detectable plasma levels for several hours in rodent studies, supported by the proline-rich sequence resisting cleavage by gastric proteases