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B 12 excretion in man: an isotope study

[1] [4] When B12 is deficient, myelin production is impaired, leading to demyelinationthe breakdown of this protective sheathwhich results in abnormal nerve signalling perceived as pain, tingling, or numbness

People with gastrointestinal conditions Conditions like celiac disease, Crohn disease, or other malabsorption syndromes already impair B12 absorption

[8] [4] The body cannot produce B12 naturally, so it must be obtained through diet (primarily animal products) or supplementation

Some functions that choline serves in the body are: Production of sphingomyelin and phosphatidylcholine, which are needed to maintain cell membrane integrity