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It has been shown that loss of Raptor activates caspase 3, leading to mitochondrial abnormalities, which positively regulate apoptosis and autophagy (101)
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Parents and caregivers have observed reduced hyperactivity, irritability, and repetitive behaviors

doi: 10.1155/2017/2549491 154 FerrariSMFallahiPDi BariFVitaRBenvengaSAntonelliA

Nakamura T, Tu S, Akhtar MW, Sunico CR, Okamoto S, Lipton SA

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