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Additionally, accelerated ATP degradation under pathological conditions (e.g., intense exercise and ischemiareperfusion injury) promotes hypoxanthine accumulation, creating a secondary drive for UA overproduction (Uskudar Cansu et al., 2019)

High-quality sourcing and clean manufacturing are essential for a molecule that is intended to support detoxification

Challenges and future directions 5.1

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Solid lines are irrelevant dsRNA treatments and dashed lines are dsTGR treatments
