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Potential Benefits of Epidural Steroid Injections Most practitioners will agree that an epidural injection can be beneficial during an acute episode of back and/or leg pain

This leads to the initiation of mitochondrial oxidative stress, which is amplified by the activation of c-Jun N-terminal kinase (JNK), resulting in mitochondrial dysfunction and opening of mitochondrial permeability transition pores

B12 Injections are considered safe, even in patients without a notable deficiency

This study design gives researchers confidence that any improvement is due to the treatment, not other factors