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For each mol of oxidized glutathione (GSSG) one mol of NADPH is required to produce GSH

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

Gold nanoparticles are possible candidates for gene therapy, drug delivery, photothermal therapy, and photodynamic therapy, especially in lung cancer and viral diseases (Mousavi-Kouhi et al., 2021b)

Approximately 80% of total iron is utilized in the synthesis of hemoglobin in erythrocytes to support physiological functions, while the rest is stored in the liver in the form of ferritin in either hepatocytes or Kupffer cells (KCs) [36]

Given that XKR8 is a caspase-3-activated phospholipid scramblase, we next investigated whether caspase-3 is involved in PMA-induced NET formation