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The Krebs or TCA cycle with its electron transport chain ETC also requires activated B2 and B3

However, phosphorylated AKT (p-AKT) and phosphorylated p38 (p-p38), the activated forms of AKT and p38, remarkably decreased in HCT116 GSTA4 cells compared with HCT116 cells, indicating inhibition of AKT and p38 signaling pathways

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