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Some drugs, including proton pump inhibitors (PPIs) and histamine 2 receptor antagonists (H2RAs) are acid-inhibiting, impairing the release of dietary B12 from food proteins, thus producing risk of B12 deficiency (Lam et al., 2013)

Vitamin B12 was initially discovered more than 70 years ago during a search for the "anti- pernicious anemia factor" found in liver extracts used to treat pernicious anemia (1,2)

Micro-dosing represents a departure from conventional approaches

However, the role of the microbiome in NNMTi-mediated weight loss is yet to be elucidated

IV Therapies & Injectables You take a multivitamin and plan meals with vegetables, protein and fiber yet you still feel tired, rundown or foggy