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Are there any ethical concerns or debates surrounding the use of placebo groups in double-blinded trials, especially in cases where effective treatments are already available

81 A study in anxious dogs showed treatment with the probiotic yeast Saccharomyces boulardii, at 1 billion CFUs per kg of dog food daily for 35 days, decreased levels of cortisol, suggesting stress reduction

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Alterations in these opposing groups of biomarkers may highlight a direct link between the loss of intestinal homeostasis and the severity of AD in adults