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We then investigated retinal function using mfERG, but NAC treatment did not ameliorate the decline in retinal function in GLAST KO mice compared with controls (Fig

Sep 2006;126(9):987-92

Yamamoto, T., Azechi, H

In addition, it needs to be established whether the differential toxicity observed in liver slices can be reproduced using isolated hepatocytes, or in other in vitro models

Supporting this, removal of microglia from tri-culture systems significantly delayed the rate and extent of iron-induced neuronal death, underscoring the essential role of microglia in mediating ferroptotic neurotoxicity (Ryan et al., 2023)
