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Journal of Clinical Investigation, 128(8), 3341-3355
Non-haemolysed serum was used according to the manufacturers protocol
Mitochondria morphological changes are associated with dysfunction and altered energy metabolism, whereby adenosine triphosphate (ATP) production is insufficient to maintain the Na+/K+-ATPase neuronal activity, which leads to massive calcium (Ca +2 ) influx followed by glutamate toxicity [24]
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