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2009;72(21 Suppl 4):S1136
This is the first study to strongly suggest that HIF-1 phosphorylation at Thr645 might improve protein stability of HIF-1 via reducing UPS degradation under hypoxic conditions, thereby offering novel insights into modified phosphorylation and ubiquitination of HIF-1
For instance: A clinical trial found that individuals supplementing with NAC exhibited increased glutathione levels in their blood, indicating enhanced synthesis and availability
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