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doi: 10.1016/j.cmi.2016.04.017 10 GlaserP.FrangeulL.BuchrieserC.RusniokC.AmendA.BaqueroF.et al

References Walker RF, et al

There was even a theory originally put out in the 1950s called The Free Radical Theory of Aging* which basically held that we age by rusting from within, due largely (but not exclusively) to free radical damage

For each emulated trial, we used a propensity score framework with baseline covariates to balance the treated and control groups 99

FGD has multiple actions at the level of the central nervous system (CNS): (i) in endothelial cells, it reduces the permeability of the bloodbrain barrier (BBB) by decreasing the expression of ICAM-1 and reducing the binding of leukocytes to endothelial cells