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It also has a growth hormone independent growth-stimulating effect, which is optimised when combined with growth hormone [4]

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Several studies have shown that METTL3 plays important regulatory roles in prostate cancer proliferation, migration, invasion, apoptosis, drug resistance androgen-induced splicing and glycolipid metabolism maintenance (125,126)

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Trends Biochem Sci 38: 592602, 2013 [DOI] [PubMed] [Google Scholar] 60

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