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Gene co-expression analysis shows upregulation of HIF-1 signaling and glycolysis-related genes

Subsequent pioneering studies led to the characterization of sulfenic acid formation in proteins

176 While it remains debated whether neuroinflammation initiates or results from neurodegeneration, systemic inflammation is known to amplify CNS pathology

Damage to mitochondrial DNA also occurs(151, 155), and variations in mitochondrial DNA are associated with different probabilities of development of severe diabetic retinopathy (156) related, at least in part, to the expression levels of particular proteins