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The ABCC8 gene is also located on chromosome 11p15.1 and is composed of 38 exons that generate five alternatively spliced mRNAs, each of which encodes a distinct protein isoform

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Six were not included here because they reviewed the available literature without reporting cases or had confounding variables of patient evaluation such as pre-existing liver disease

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Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice

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