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Future efforts should leverage integrated multi-omics and single-cell sequencing to systematically map the ferroptosis-cuproptosis interactome in OSCC, identify master regulatory nodes, and stratify patients most likely to benefit from such therapies

Moreover, precision medicine grounded in artificial intelligence and big data is also anticipated to reshape the treatment decisionmaking paradigm

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Bleaching or skin lightening creams or ointments are widely used worldwide either to attempt to remove localised dark patches or as a fashion trend aiming to reduce normal melanin in the skin

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