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The absolute risk increase for diabetic retinopathy complications was greater among patients with a history of diabetic retinopathy at baseline (semaglutide 8.2%, placebo 5.2%) than among patients without a known history of diabetic retinopathy (semaglutide 0.7%, placebo 0.4%)

136 Because of the unpredictability of an idiosyncratic reaction and the low incidence of occurrence, a cause-and-effect relationship is difficult to establish

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doi: 10.1016/j.yexcr.2021.112515

[DOI] [PubMed] [Google Scholar] 282.Tecklenburg S.L., Mickleborough T.D., Fly A.D., Bai Y., Stager J.M