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This is not just cosmeticvisceral fat is metabolically active and strongly linked to insulin resistance, fatty liver, and cardiovascular disease

When noise and ototoxic drugs cause SGN damage, Ca 2+ influx is exacerbated and the intracellular Ca 2+ concentrations increase, thereby initiating the apoptotic program [126]

Integrated analysis of multi-omics data: integration of metagenomic sequencing technology, untargeted metabolomics analysis, and detailed clinical phenotype data should construct systems biology network models of microecology-metabolite-disease interactions (162)

Lingwood& Simons, 2010)

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