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A possible mechanism to understand how Pycnogenol contributes to lower glucose blood levels could be that sugar absorption was slowed down in patients supplemented with Pycnogenol by inhibition of -glucosidase, the enzyme that disassembles starch (64)

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ROS are modulated in normal conditions by different elements, including enzymes of the antioxidant defence, which prevent the harmful effects of ROS on the tissue (7, 10)

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