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In line with MHRA advice, metformin should generally be continued while B12 deficiency is investigated and treated, given its important role in diabetes management

Adverse effects: Seek medical advice if you develop any unusual, severe, or persistent side effects or symptoms after taking vitamin B12 supplements

Sulfhydryl compounds may mediate gastric cytoprotection

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DSIP is a neuropeptide with a different mechanism of action it is studied for its broader influence on sleep architecture, stress hormone regulation, and neurotransmitter activity rather than simply sleep timing