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While the number of SOREMP is an established marker for narcolepsy our SGB model gives a new unexpected predictor, the mean REM sleep latency

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Biguanides (Metformin) The biguanides are a class of drug that functions to lower serum glucose levels by enhancing insulin-mediated suppression of hepatic glucose production and enhancing insulin-stimulated glucose uptake by skeletal muscle

Retatrutide is an investigational triple hormone agonist (GLP-1, GIP, glucagon) showing promising early results for obesity and type 2 diabetes, while tirzepatide is an FDA-approved dual agonist (GLP-1, GIP) available for use today

[DOI] [PubMed] [Google Scholar] 15.Knapik JJ, Steelman RA, Hoedebecke SS, Austin KG, Farina EK, Lieberman HR