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10.1002/dmrr.3060 82 HamadaY.FujiiH.FukagawaM

Therefore, this study was aimed to explore whether BA could prevent hippocampal neuronal apoptosis and increase seizure threshold throughout the improvement of antioxidant levels in KA-induced oxidative stress in a mouse model of epilepsy

Taleb et al., 2018)

Interestingly, copper accumulation in ATP7B -deficient hepatic cells increases the expression of PRNP through the transcription factor MTF1 [61,62,63], thus forming a positive feedback loop that amplifies copper overload under the pathological condition