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The authors thank Marie Fleisner of the Marshfield Clinic Research Foundations Office of Scientific Writing and Publication for editorial support in the preparation of this manuscript

Anecdotal reports from research subjects and biohacking communities describe body composition improvements, increased subjective energy and mental clarity, and minimal side effects, though these uncontrolled observations require cautious interpretation and cannot substitute for rigorous clinical trials

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A vitamin B12 injection may help restore balance and support overall wellbeing when used appropriately.