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Description
Major depressive disorder
Cytosolic and mitochondrial glutathione peroxidases (cGPXs or GPX1) reduce only soluble hydroperoxides, such as H 2 O 2 , and some organic hydroperoxides, such as hydroperoxy fatty acids, cumene hydroperoxide or t-butyl hydroperoxide

It has been detected in the saliva and plasma of humans and has been shown to play a role in preventing toxicity of certain drugs in mammalian cells (2527)

Cell (2021)

Gibbs ET, Lerner II, Watson CA, Wong MA, Gerencser H-S, Brand AA MD (2023) Site IQ in mitochondrial complex I generates S1QEL-sensitive superoxide/hydrogen peroxide in both the reverse and forward reactions
