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Although low concentrations of NO are essential for motility and the capacitation process, high concentrations of NO can induce DNA damage in different ways [59]
[DOI] [PMC free article] [PubMed] [Google Scholar] Coleman J
doi: 10.1016/j.trecan.2021.04.003 212 SuzukiSTanakaTPoyurovskyMVNaganoHMayamaTOhkuboSet al
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Till date, systemic skin whitening agents do not have much scientific evidence regarding their use and strict laws should be enforced to ban the use of these agents until well conducted randomized controlled trials are available ensuring the safety and efficacy of these agents
