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Description
The most common cause of methaemoglobinaemia is exposure to an oxidising agent, such as in nitrite poisoning, however it can also be caused by a variety of genetic defects affecting both red cell metabolism and Hb structure 3
His-561 is equivalent to His-262 in IdeS and gasMac-1, where the N 2 atom of the side chain forms a hydrogen bond with the S atom of Ser/Cys-94
However, while correlation of nerve fiber loss with the degree of neuropathy has been attempted in several conditions, and functional deficits arising from axon degeneration appear intuitive, the contribution of demyelination and peripheral nerve degeneration to the pathobiology of CIPN is not entirely clear
[DOI] [PMC free article] [PubMed] [Google Scholar] 140.Schnorr C.E., Morrone Mda S., Simes-Pires A., Bittencourt Lda S., Zeidn-Chuli F., Moreira J.C
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