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This substance not only protects cells from environmental aggressors but also acts directly on the melanogenesis process, helping the skin regain its natural glow

Extracellular mtDNA could engage pattern recognition receptors (PRR) on microglia, astrocytes, and infiltrating immune cells, serving as a potent pro-inflammatory signal that drives neuroinflammation in acute brain injury, ischemia, and chronic NDDs

10.1021/jf204447y 73 HopkinsA

Canakinumab, a monoclonal antibody that targets IL-1, reduced inflammatory markers and cardiovascular events in patients with prior myocardial infarction [23]
