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By acting on MT1 and MT2 receptors located on hypothalamic GnRH neurons, the pituitary gland, and the ovaries, it participates in regulating pulsatile GnRH secretion, the release of gonadotropins [luteinizing hormone (LH) and follicle-stimulating hormone (FSH)], and ovarian steroidogenesis ( Melatonin exerts protective effects on ovarian cells by acting as an antioxidant, thereby preserving their optimal physiological condition, which is essential for reproductive health (Figure 4)

Badri, P

Increased plasma bradykinin level is associated with cognitive impairment in Alzheimers patients