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Description
Association between metformin and vitamin B12 deficiency in patients with type 2 diabetes: A systematic review and meta-analysis

Chunhua Huang and Cheng Lyu did the experiments
Vitamin B12 The stomach acids that aid in the natural breakdown of food also break down vitamin B12 pill supplements, the body will only absorb a small amount when ingested orally

Neurotransmitters

As B 12 deficiency constrained in myelination, child develops varied cognitive and intellectual problems depending upon the area of the nervous system affected (Graber et al., 1971)