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3.3.2 TIM-3 as a potential target TIM-3 is another checkpoint that negatively regulates T cell responses

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Clinically significant effects include hepatoprotection during acetaminophen toxicity, reduction of chronic bronchitis exacerbations, and potential modulation of neuroinflammation through glutamate regulation

Moreover, recent studies have shown that GSTA4 expression is selectively downregulated in adipose tissue of obese insulin-resistant C57BL/6J mice and in human obesity-linked insulin resistance (Curtis et al., 2010)

doi: 10.3389/fncel.2024.1360195