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10.1016/j.cyto.2012.03.027 235 WarwickR

Abdala-Valenzia et al

In addition, ZIP8-knockout mice display impaired iron recycling during inflammation, elevated splenic iron and reduced serum iron, highlighting ZIP8s role in systemic metal handling 175

4, the network consists of a complex interconnected web with a number of differentially expressed proteins present at key hubs, and some of them function in a variety of cellular processes (Table 1)

The epidermal layer is highly cellular, comprising primarily keratinocytes, whilst the dermal layer comprises fibroblasts which secrete collagen fibers, the major component of the dermis [23]