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Two papers published back-to-back in Nature 2019 suggest that FSP1 overexpression in cells significantly protects them from ferroptosis-inducing factors and that this process is not dependent on GPX4 [98, 99]

[DOI] [PMC free article] [PubMed] [Google Scholar] 246.Ketelut-Carneiro N., Fitzgerald K.A

Consistent with increased PPP flux, clear cell renal cell carcinoma (ccRCC) tumors display significant accumulation of reduced GSH and PPP-related metabolites (Li et al., 2014a)

& Waseem, N