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Unique Benefits: Binds to nitric oxide (NO), which inhibits the methylation cycle and contributes to oxidative stress in ME/CFS and fibromyalgia

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In other words, it is unknown if the net effect of the diminished presynaptic synthesis on the one hand and the decreased reuptake increased postsynaptic reception on the other hand result in an increase or decrease of the inhibitory tone on pyramidal cells by GABAergic neurons (63)

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