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Therefore, the selective and almost exclusive release of the drug to the action site would lead to considerable therapeutic advantage

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Configurations of 2.1- and 2.7-fold increased oral bioavailability in animal models were achieved using binary or ternary solid dispersions ( 5.4 Phytosomes/phospholipid complexes Phytosomes are complexes of plant bioactives with phospholipids (usually phosphatidylcholine), typically of the amphiphilic type with augmented solubility and penetration properties
Worse, they impair the very systems your body relies on to get rid of them, making detoxification harder the longer they stick around

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