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Therefore increased monitoring of valproate and concomitant drug concentrations and dosage adjustment are indicated whenever enzyme-inducing or inhibiting drugs are introduced or withdrawn (7.1) Aspirin, carbapenem antibiotics, estrogen-containing hormonal contraceptives: Monitoring of valproate concentrations is recommended (7.1) Co-administration of valproate can affect the pharmacokinetics of other drugs (e.g

The results of the cell experiments showed that API (25, 50, and 100 M) improved lipid accumulation to varying degrees compared with the model group ( 4.6 Others Furthermore, in HFD-induced mice, API (0.005% w/w) reduced plasma levels of free fatty acids, total cholesterol, apolipoprotein B, and liver function markers, while ameliorating hepatic steatosis and liver hypertrophy (Table 3

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Kaempferol reduces obesity, prevents intestinal inflammation, and modulates gut microbiota in high-fat diet mice

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