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Training method The EX and EXIN groups were adapted to treadmill training intensity of 12 m/min, 8 slope for 3 days

In support of this, in a dual-hit genetic-environmental mouse model of SCZ, where DISC1 mutation was combined with MIA, transient administration of minocycline, an anti-inflammatory antibiotic drug, rescued electrophysiological and structural deficits during early postnatal development, as well as cognitive abilities in juvenile mice (Chini et al., 2020)

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Bioinformatic analysis revealed insulin signaling pathway key molecules being affected in AD patients of which the six kinases, leucine-rich repeat kinase 2 (LRRK2), glycogen synthase kinase 3 beta (GSK3B), AKT serine/threonine kinase 1 (AKT1), epidermal growth factor receptor (EGFR), mitogen-activated protein kinase 1 (MAPK1), and the non-receptor tyrosine kinase FYN, played central roles [56]

Dong LM, Wilson C, Wardell MR, Simmons T, Mahley RW, Weisgraber KH, et al