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International Journal of Molecular Sciences, 18 (11), Article 2331

In addition, a non-enzymatic product of the prostaglandin D2 synthase gene ( PGD2S ), whose expression is upregulated by acetylcarnitine treatment with 100 mg/kg body weight [134], has been shown to have anti-inflammatory properties that may help protect the brain from ischemiareperfusion injury [72]

doi: 10.1038/s41467-021-23762-0

Caffeine contained in EDs also enters into pharmacodynamic interactions of both synergism and antagonism
