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Description
CREB binds cAMP response elements (CRE) in genomic DNA causing the transcription of various genes including those encoding for steroidogenic enzymes (e.g., aromatase) and cholesterol transport, the precursor substrate for sex steroid synthesis (e.g., steroidogenic acute regulatory protein, StAR)
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Summary: Metformin and Trulicity can be taken together for type 2 diabetes management, but neither is licensed specifically for weight loss in non-diabetic individuals
To locate the ventrogluteal site, place the patient in a supine or lateral position
